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13597 details
Primary information
ID13597
Uniprot IDQ9WUG6
DescriptionInsulin-like peptide INSL5 (Insulin-like peptide 5) (Relaxin/insulin-like factor 2) (Relaxin/insulin-like protein) [Cleaved into- Insulin-like peptide INSL5 B chain; Insulin-like peptide INSL5 A chain]
OrganismMus musculus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus (Mouse)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the insulin family.
Tissue SpecificityHighest expression in colon with lower levels in thymus. Minimal levels in testis.
Post Translational ModificationNA
FunctionMay have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor.
Length135
Molecular Weight15
NameInsulin-like peptide INSL5 B chain
SequenceQTVKLCGLDYVRTVIYICASSRW
Sequence map23-46
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA