Detailed description page of Hmrbase2

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13581 details
Primary information
ID13581
Uniprot IDQ9Y5Q6
DescriptionInsulin-like peptide INSL5 (Insulin-like peptide 5) [Cleaved into- Insulin-like peptide INSL5 B chain; Insulin-like peptide INSL5 A chain]
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the insulin family.
Tissue SpecificityHighly expressed in rectum with lower levels in uterus and ascending and descending colon.
Post Translational ModificationNA
FunctionMay have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor.
Length135
Molecular Weight15
NameNA
SequenceNA
Sequence mapNA
PDB ID2K1V; 2KBC;
DrugpediaNA
ReceptorQ8TDU9
DomainNA
Pharmaceutical UseNA