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13544 details
Primary information
ID13544
Uniprot IDQ62598
DescriptionDentin sialophosphoprotein [Cleaved into- Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)]
OrganismRattus norvegicus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat)
Subcellular LocationSecreted; extracellular space; extracellular matrix.
Developmental StageNA
SimilarityNA
Tissue SpecificitySpecifically expressed in teeth; mainly in odontoblasts and transiently in pre-ameloblasts.
Post Translational ModificationDSP is glycosylated.
FunctionDSP may be an important factor in dentinogenesis. DPP may bind high amount of calcium and facilitate initial mineralization of dentin matrix collagen as well as regulate the size and shape of the crystals.
Length687
Molecular Weight70
NameDentin sialophosphoprotein
SequencePVPQLVPLERDIVEKSADVPFLAHPGTAAQNELHINNATNDDSPKGSELGRQVHSNGGYERDRNGSESIAVGGKSSPTQPILANAQGNSAKEREDVETYGHDGIHAGGENSTANGIRGQVGIAENAEEAKESKVHGQPHQDTKTGLASDTSQNGDATLVQENEPQVAGSKNSTNHEVGTHGSGVAAQETTPQREGEGSENQGAEVTPSIGEGAGLDNTEGSPSGNGIEEDEDTGSGDGVGADAGDGRESHDGTEGHEGQSSGGNNDNRGQGSVSTEDDDSKEQEGSPNGRGGDNTSSSEETGIEEGDGTQTTQDNQNLSPTEGGIISQAEACPSGQSQNQGLETEGSSTGNKSSITKESGKLSGSKDSNGHHGMELDKRNSPKQGESDKPQGAAEKSDTHNNMGHSRIGSSSNSDGHDSYDFDDESMQGDDPNSSDESNGSDGSDDANSESAIENGNHGDASYTSDESSDNGSDSDSHAGEDDSSDDTSDTDDSDSNGDDDSESKDKDESDNSNHDNDSDSESKSDSSDSDSDSSDSSDSSDSSDSSETSDSSDSSDTSDSSDSSDSSDSSNSSDTSDSSDSSDGDSSDGDSSDSDSSDSDSSNSSDSDSSDSSDSSSSDSSDSDSDSKDSTSDSSDDNSKSGNGNSDSDSDSDSDSEGSDSNHSTSDD
Sequence map29-27
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA