| Primary information |
|---|
| ID | 13531 |
| Uniprot ID | P51460 |
| Description | Insulin-like 3 (Leydig insulin-like peptide) (Ley-I-L) (Relaxin-like factor) [Cleaved into- Insulin-like 3 B chain; Insulin-like 3 A chain] |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the insulin family. |
| Tissue Specificity | Expressed in prenatal and postnatal Leydig cells. Found as well in the corpus luteum; trophoblast; fetal membranes and breast. |
| Post Translational Modification | NA |
| Function | Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor. |
| Length | 131 |
| Molecular Weight | 14 |
| Name | NA |
| Sequence | NA |
| Sequence map | NA |
| PDB ID | 2H8B; 2K6T; 2K6U; |
| Drugpedia | NA |
| Receptor | Q8WXD0 |
| Domain | NA |
| Pharmaceutical Use | NA
|