| Primary information |
|---|
| ID | 13528 |
| Uniprot ID | A0A0B5ABD9 |
| Description | Con-Ins G2 (Insulin 2) [Cleaved into- Con-Ins G2 B chain; Con-Ins G2 A chain] |
| Organism | Conus geographus |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Mollusca; Gastropoda; Caenogastropoda; Neogastropoda; Conoidea; Conidae (cone shells); Conus; Gastridium; Conus geographus (Geography cone) (Nubecula geographus) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the insulin family. |
| Tissue Specificity | Expressed by the venom gland. |
| Post Translational Modification | NA |
| Function | This venom insulin; from a fish-hunting cone snail; facilitates prey capture by rapidly inducing hypoglycemic shock. Intraperitoneal injection of this peptide into zebrafish lowers blood glucose with the same potency than human insulin. In vivo; when applied to water; this peptide reduces overall locomotor activity of zebrafish larvae; observed as a significant decrease in the percentage of time spent swimming and movement frequency. |
| Length | 130 |
| Molecular Weight | 14 |
| Name | NA |
| Sequence | NA |
| Sequence map | NA |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|