Detailed description page of Hmrbase2

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13517 details
Primary information
ID13517
Uniprot IDP01021
DescriptionBradykinin-potentiating and C-type natriuretic peptides (Angiotensin-converting enzyme inhibitor) (BPP-CNP homolog) [Cleaved into- Blomhotin; Bradykinin-potentiating peptide A (BPP-a) (Potentiator A); Leu3-blomhotin (Potentiator D); Bradykinin-potentiating peptide B (BPP-b) (Potentiator B); Bradykin
OrganismGloydius blomhoffii
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria (diapsids); Lepidosauria (lepidosaurs); Squamata (squamates); Bifurcata (split-tongued squamates); Unidentata; Episquamata; Toxicofera; Serpentes (snakes); Colubroidea; Viperidae; Crotalinae (pit vipers); Gloydius; Gloydius blomhoffii (Mamushi) (Agkistrodon ha
Subcellular LocationSecreted
Developmental StageNA
SimilarityIn the N-terminal section; belongs to the bradykinin-potentiating peptide family.
Tissue SpecificityExpressed by the venom gland.
Post Translational ModificationNA
Function[Blomhotin]- inhibits the rabbit lung angiotensin-converting enzyme (ACE) (IC(50)=15 uM)
Length263
Molecular Weight27
NameNA
SequenceNA
Sequence mapNA
PDB ID4AA2; 4APJ;
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA