| Primary information |
|---|
| ID | 13506 |
| Uniprot ID | Q7T3L1 |
| Description | Kininogen-1a [Cleaved into- Maximakinin (Bombinakinin M); Bradykinin; Bombinakinin-GAP (Bombinakinin M gene-associated protein)] |
| Organism | Bombina maxima |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amphibia; Batrachia; Anura; Bombinatoridae; Bombina (firebellied toads); Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the bradykinin-related peptide family. |
| Tissue Specificity | Expressed by the skin glands. |
| Post Translational Modification | NA |
| Function | [Bombinakinin-GAP]- plays a role in the control of feeding by the brain; intracerebroventricular administration of the peptide induced significant decrease in food intake in rats. Inhibits the bradykinin-induced in vitro relaxation of rat arterial smooth muscle. May target bradykinin receptors (BDKRB). |
| Length | 294 |
| Molecular Weight | 33 |
| Name | Kininogen-1a |
| Sequence | ERNVPESEEKTEQFLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDMYEIKQYKTAHGRPPICAPGEQCPIWVGK |
| Sequence map | 28-54 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|