| Primary information |
|---|
| ID | 13489 |
| Uniprot ID | Q9ULZ1 |
| Description | Apelin (APJ endogenous ligand) [Cleaved into- Apelin-36; Apelin-31; Apelin-28; Apelin-13] |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the apelin family. |
| Tissue Specificity | Expressed in the brain with highest levels in the frontal cortex; thalamus; hypothalamus and midbrain (PubMed-10617103). Secreted by the mammary gland into the colostrum and the milk. |
| Post Translational Modification | Several active peptides may be produced by proteolytic processing of the peptide precursor. |
| Function | Endogenous ligand for the apelin receptor (APLNR) |
| Length | 77 |
| Molecular Weight | 8 |
| Name | NA |
| Sequence | NA |
| Sequence map | NA |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | P35414; P35414; P35414; P35414 |
| Domain | NA |
| Pharmaceutical Use | NA
|