Primary information |
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ID | 13473 |
Uniprot ID | Q8AUU1 |
Description | Ghrelin [Cleaved into- Ghrelin-12; Ghrelin-19] |
Organism | Carassius auratus |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Otomorpha; Ostariophysi; Otophysi; Cypriniphysae; Cypriniformes (carps and others); Cyprinoidei; Cyprinidae; Cyprininae; Carassius; Carassius auratus (Goldfish) |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | Belongs to the motilin family. |
Tissue Specificity | Expressed in the telencephalon; hypothalamus; pituitary; intestine; liver; spleen and gill; with expression strongest in the intestine. |
Post Translational Modification | O-octanoylation or O-decanoylation is essential for activity. The O-decanoylated form differs in the length of the carbon backbone of the carboxylic acid forming an ester bond with Ser-29. |
Function | Ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Has an appetite-stimulating effect. |
Length | 103 |
Molecular Weight | 11 |
Name | NA |
Sequence | NA |
Sequence map | NA |
PDB ID | NA |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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