Detailed description page of Hmrbase2

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13473 details
Primary information
ID13473
Uniprot IDQ8AUU1
DescriptionGhrelin [Cleaved into- Ghrelin-12; Ghrelin-19]
OrganismCarassius auratus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Otomorpha; Ostariophysi; Otophysi; Cypriniphysae; Cypriniformes (carps and others); Cyprinoidei; Cyprinidae; Cyprininae; Carassius; Carassius auratus (Goldfish)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the motilin family.
Tissue SpecificityExpressed in the telencephalon; hypothalamus; pituitary; intestine; liver; spleen and gill; with expression strongest in the intestine.
Post Translational ModificationO-octanoylation or O-decanoylation is essential for activity. The O-decanoylated form differs in the length of the carbon backbone of the carboxylic acid forming an ester bond with Ser-29.
FunctionLigand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Has an appetite-stimulating effect.
Length103
Molecular Weight11
NameNA
SequenceNA
Sequence mapNA
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA