Primary information |
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ID | 13471 |
Uniprot ID | E7EZ53 |
Description | Galanin peptides [Cleaved into- Galanin; Galanin message-associated peptide] |
Organism | Danio rerio |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Otomorpha; Ostariophysi; Otophysi; Cypriniphysae; Cypriniformes (carps and others); Cyprinoidei; Danionidae; Danioninae; Danio; Danio rerio (Zebrafish) (Brachydanio rerio) |
Subcellular Location | Secreted |
Developmental Stage | In embryos and larvae; detected mainly in nerve cells in the preoptic-hypothalamic regions and fibers innervating several brain regions (at protein level) (PubMed-22522977; PubMed-27315774). In embryo |
Similarity | Belongs to the galanin family. |
Tissue Specificity | Strongly expressed in brain and stomach; moderately in the eye; and very weakly in heart; kidney and gills. Not detected in liver. |
Post Translational Modification | NA |
Function | Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1 (galr1a and galr1b) and GALR2 (galr2a and galr2b). This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract; growth hormone and insulin release and adrenal secretion. |
Length | 118 |
Molecular Weight | 12 |
Name | NA |
Sequence | NA |
Sequence map | NA |
PDB ID | NA |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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