| Primary information |
|---|
| ID | 13471 |
| Uniprot ID | E7EZ53 |
| Description | Galanin peptides [Cleaved into- Galanin; Galanin message-associated peptide] |
| Organism | Danio rerio |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Otomorpha; Ostariophysi; Otophysi; Cypriniphysae; Cypriniformes (carps and others); Cyprinoidei; Danionidae; Danioninae; Danio; Danio rerio (Zebrafish) (Brachydanio rerio) |
| Subcellular Location | Secreted |
| Developmental Stage | In embryos and larvae; detected mainly in nerve cells in the preoptic-hypothalamic regions and fibers innervating several brain regions (at protein level) (PubMed-22522977; PubMed-27315774). In embryo |
| Similarity | Belongs to the galanin family. |
| Tissue Specificity | Strongly expressed in brain and stomach; moderately in the eye; and very weakly in heart; kidney and gills. Not detected in liver. |
| Post Translational Modification | NA |
| Function | Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1 (galr1a and galr1b) and GALR2 (galr2a and galr2b). This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract; growth hormone and insulin release and adrenal secretion. |
| Length | 118 |
| Molecular Weight | 12 |
| Name | NA |
| Sequence | NA |
| Sequence map | NA |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|