| Primary information |
|---|
| ID | 13461 |
| Uniprot ID | Q7Z4H4 |
| Description | Protein ADM2 (Intermedin) [Cleaved into- Adrenomedullin-2 (AM2) (Intermedin-long) (IMDL); Intermedin-short (IMDS)] |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the adrenomedullin family. |
| Tissue Specificity | Expressed in the esophagus; stomach; jejunum; ileum; ileocecum; ascending colon; transverse colon; descending colon and rectum. Expressed in myocardial cells of the heart; renal tubular cells; hypotha |
| Post Translational Modification | NA |
| Function | [Adrenomedullin-2]- May play a role as physiological regulators of gastrointestinal; cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway. |
| Length | 148 |
| Molecular Weight | 15 |
| Name | NA |
| Sequence | NA |
| Sequence map | NA |
| PDB ID | 6D1U; 6UVA; |
| Drugpedia | NA |
| Receptor | Q16602 |
| Domain | NA |
| Pharmaceutical Use | NA
|