Detailed description page of Hmrbase2

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13444 details
Primary information
ID13444
Uniprot IDP23582
DescriptionC-type natriuretic peptide [Cleaved into- CNP-22; CNP-29; CNP-53]
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the natriuretic peptide family.
Tissue Specificity[CNP-22]- In the kidney; predominantly expressed in the distal tubular cells (at protein level).
Post Translational Modification[CNP-22]- Degraded by IDE (in vitro).
Function[CNP-22]- Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic
Length126
Molecular Weight13
NameNA
SequenceNA
Sequence mapNA
PDB ID1JDP;
DrugpediaNA
ReceptorP20594
DomainNA
Pharmaceutical UseNA