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13438 details
Primary information
ID13438
Uniprot IDP0C7W1
DescriptionProsalusin (Torsin family 2 member A) (Torsin-2A) [Cleaved into- Salusin-alpha; Salusin-beta]
OrganismBos taurus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos (oxen; cattle); Bos taurus (Bovine)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the ClpA/ClpB family. Torsin subfamily.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionSalusin may be a endocrine and/or paracrine factor able to increase intracellular calcium concentrations and induce cell mitogenesis. Salusin may also be a potent hypotensive peptide.
Length242
Molecular Weight26
NameProsalusin
SequenceWDLSSLRCNFGSFCECDFQPDFQGLECDLAQHLAGQHLARSLVVKALKAFLQDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFRDGLRSPHVHHFSPVIHFPHPSHLERYKKDLKSWVQGNLTVCSRSLFLFDEMDKLAPGLIEVLRPFLGSSWVVYGTNYRKAIFIFIRWLLALGHHGRASPGRSGALPATPAAPRAALCAQRAGPSGPGAQG
Sequence map31-02
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA