Primary information |
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ID | 13415 |
Uniprot ID | Q27309 |
Description | Vitellogenin [Cleaved into- Vitellin light chain (VL); Vitellin light chain rare isoform; Vitellin heavy chain rare isoform; Vitellin heavy chain (VH)] |
Organism | Bombyx mori |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota (winged insects); Neoptera; Endopterygota; Amphiesmenoptera; Lepidoptera (butterflies and moths); Glossata; Neolepidoptera; Heteroneura; Ditrysia; Obtectomera; Bombycoidea (hawk-moths); Bombycidae (silkworm moths); Bombycinae; Bombyx; Bombyx mori (Silk moth) |
Subcellular Location | Secreted |
Developmental Stage | First detected in the female fat body on day-2 of spinning stage; reaching maximal levels at larval-pupal ecdysis and declining thereafter. Not found in the male tissues. |
Similarity | NA |
Tissue Specificity | Produced by the fat body; where it is cleaved before being secreted into hemolymph. Sequestered then by a single class of receptor mediated endocytosis in the ovary. |
Post Translational Modification | Glycosylated and phosphorylated. |
Function | Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development. |
Length | 1782 |
Molecular Weight | 203 |
Name | Vitellogenin |
Sequence | RFSSQSQSTGGQTYPSPWQVGKQYRYEVTSRTLAHLQEGPSSGSAFKAQFTIRVKSPGRLQAKLENPQHGNFNEQLPDPRELPVDLKYQPTPNIDKVFEIEIDGGRIVSLDFPTSVPVPQENLIKGLISALQLDTSAHRVIHDSQNNYDREQQQGLFRKMETDVTGDCETLYTVSPVASEWRRELPKFANEQDPVEVTKSTNYGHCHHRVAYHFGVPVGAEWTGTAHKTQEQQLIGRATYSRILTGKEGPIYKAETTSTVHVHPHLYGKQKAEVYSHVHMELISVDQDSGAEWPRAGAMRPAQSILYSLSTKQMTKHYESSSSSSSSESHEFNFPEQHEHPHQSNQRSRRSYMRSKLVTVHKVLKKRNSESSSGSSSSSADSSSTYINDDIPDIDEPAYAALYMSPQPHADKKQNAMNAQKILQDIAQQLQNPNNMPKSDFLSKFNILVRLIASMSTEQLSQTSRSIETAKTSNNIIKSDMWMIFRDGVTQAGTLPAFKQIQSWIENKKIQEEEAAQVVVALPRTLRYPTKQIMTQFFNFARSPAVKDQMFLNSSALMAATKLINLGQVNNYTAHSYYPTHMYGRLTHKHDAFVLEEILPTLAADLKATVEYKDSTKAQVYIQAIGNLGHREILKVFAPYLEGKVEISTYLRTHIVKNLKTLAKLRDRHVRAVLFSILRNTAEPYPVRVAAIQSIFISHPTGEMMQAMAEMTHNDPSVEVRAVLKSAILSAAELQHPRNFYLSRTAQAARYLVTNEEFGYQHSFKFIDDSYDEDNDIGTFVISHIGSEDSLLPKDFKIVTNSKGGAWERNTIEASFSSAERFLDYLRDSVFAPHPKFDRAHKYSAEKIAKLLNIKNDEEEPLEASFYVDFMNNQRLFSFSESDLQQLSQYISEYMKKVESGAEKHYTKVYNQDQVSIMFPVASGMPFIFKYKEPAVIHFQSKLKGKFSFPSKDNKYYEANMIKDVQFTYAINIDGNVGFMDTLSNQYSSVGVVNKLQFNIPFKFGIEIKSGLIKFRVEPLHPDQDQTLVHYSVWPYSASQKKDSLVAISQDPATKIVERRSKVFSVDSKYGQSTHAVIYAQGYTYSSDWRNFGAKFTSRDYFTNLASLLTQEDIALTHFNLKHLCKQSQSKALTITAYYDEYYNQQNSGILTDATDRNDLSPNSETRRAEMVKLVSAGINKARVRVVDLSASFEGSQDQNYVLTGTWGDSPVDSKVQGMLFAGTKSATQGNQQINAVFATTKPEIHSLSFSKPLQSDLRAPFGMHFKYGQSGEIRVSGSFDRTKKYTTELENHPLAKQCSQQTTLNNFYQDSCHKAIVMAHAPDHVEFSVSFQDMSPQYRNFSYHTYRLYEYLGYWYTEANPLKLTQNGKMDFKIDFSYFDRTYTVDIASPSGEARMRDMPIATMAPGALSFYQPLKAYELVANYFTGHQYQPYCSIDGTRIHTFSNRSYEYPLSRSWHVVMQDESTQRGNWHELAILSRRQQRDQQEIYISYKSESGQDLEIEIQPASGDSAYQVKVTTNTKKITDDDLTMYWDDVKEQPFLQYHTHKDGVLVINIEDDRIRAIYDGQRFVVFTQDYRNSTRGICGRMSGEQRDDYLTPEGLVDKPELYAAAYSLNEENSDPKTQELKALATQQAYYPEYKYTSILRSDPTWQEESQSCGEDQWQSETVYKSRSYDKHKGACEVRQQVQFYENHGDICITTSRVPSCQSHCRAGDYKIQHVQVTCKSKLDHDFRMYKEQIKKGQNPEVSGIPSVKQFKVPVTCQP |
Sequence map | 45-42 |
PDB ID | NA |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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