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13415 details
Primary information
ID13415
Uniprot IDQ27309
DescriptionVitellogenin [Cleaved into- Vitellin light chain (VL); Vitellin light chain rare isoform; Vitellin heavy chain rare isoform; Vitellin heavy chain (VH)]
OrganismBombyx mori
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota (winged insects); Neoptera; Endopterygota; Amphiesmenoptera; Lepidoptera (butterflies and moths); Glossata; Neolepidoptera; Heteroneura; Ditrysia; Obtectomera; Bombycoidea (hawk-moths); Bombycidae (silkworm moths); Bombycinae; Bombyx; Bombyx mori (Silk moth)
Subcellular LocationSecreted
Developmental StageFirst detected in the female fat body on day-2 of spinning stage; reaching maximal levels at larval-pupal ecdysis and declining thereafter. Not found in the male tissues.
SimilarityNA
Tissue SpecificityProduced by the fat body; where it is cleaved before being secreted into hemolymph. Sequestered then by a single class of receptor mediated endocytosis in the ovary.
Post Translational ModificationGlycosylated and phosphorylated.
FunctionPrecursor of the egg-yolk proteins that are sources of nutrients during embryonic development.
Length1782
Molecular Weight203
NameVitellogenin
SequenceRFSSQSQSTGGQTYPSPWQVGKQYRYEVTSRTLAHLQEGPSSGSAFKAQFTIRVKSPGRLQAKLENPQHGNFNEQLPDPRELPVDLKYQPTPNIDKVFEIEIDGGRIVSLDFPTSVPVPQENLIKGLISALQLDTSAHRVIHDSQNNYDREQQQGLFRKMETDVTGDCETLYTVSPVASEWRRELPKFANEQDPVEVTKSTNYGHCHHRVAYHFGVPVGAEWTGTAHKTQEQQLIGRATYSRILTGKEGPIYKAETTSTVHVHPHLYGKQKAEVYSHVHMELISVDQDSGAEWPRAGAMRPAQSILYSLSTKQMTKHYESSSSSSSSESHEFNFPEQHEHPHQSNQRSRRSYMRSKLVTVHKVLKKRNSESSSGSSSSSADSSSTYINDDIPDIDEPAYAALYMSPQPHADKKQNAMNAQKILQDIAQQLQNPNNMPKSDFLSKFNILVRLIASMSTEQLSQTSRSIETAKTSNNIIKSDMWMIFRDGVTQAGTLPAFKQIQSWIENKKIQEEEAAQVVVALPRTLRYPTKQIMTQFFNFARSPAVKDQMFLNSSALMAATKLINLGQVNNYTAHSYYPTHMYGRLTHKHDAFVLEEILPTLAADLKATVEYKDSTKAQVYIQAIGNLGHREILKVFAPYLEGKVEISTYLRTHIVKNLKTLAKLRDRHVRAVLFSILRNTAEPYPVRVAAIQSIFISHPTGEMMQAMAEMTHNDPSVEVRAVLKSAILSAAELQHPRNFYLSRTAQAARYLVTNEEFGYQHSFKFIDDSYDEDNDIGTFVISHIGSEDSLLPKDFKIVTNSKGGAWERNTIEASFSSAERFLDYLRDSVFAPHPKFDRAHKYSAEKIAKLLNIKNDEEEPLEASFYVDFMNNQRLFSFSESDLQQLSQYISEYMKKVESGAEKHYTKVYNQDQVSIMFPVASGMPFIFKYKEPAVIHFQSKLKGKFSFPSKDNKYYEANMIKDVQFTYAINIDGNVGFMDTLSNQYSSVGVVNKLQFNIPFKFGIEIKSGLIKFRVEPLHPDQDQTLVHYSVWPYSASQKKDSLVAISQDPATKIVERRSKVFSVDSKYGQSTHAVIYAQGYTYSSDWRNFGAKFTSRDYFTNLASLLTQEDIALTHFNLKHLCKQSQSKALTITAYYDEYYNQQNSGILTDATDRNDLSPNSETRRAEMVKLVSAGINKARVRVVDLSASFEGSQDQNYVLTGTWGDSPVDSKVQGMLFAGTKSATQGNQQINAVFATTKPEIHSLSFSKPLQSDLRAPFGMHFKYGQSGEIRVSGSFDRTKKYTTELENHPLAKQCSQQTTLNNFYQDSCHKAIVMAHAPDHVEFSVSFQDMSPQYRNFSYHTYRLYEYLGYWYTEANPLKLTQNGKMDFKIDFSYFDRTYTVDIASPSGEARMRDMPIATMAPGALSFYQPLKAYELVANYFTGHQYQPYCSIDGTRIHTFSNRSYEYPLSRSWHVVMQDESTQRGNWHELAILSRRQQRDQQEIYISYKSESGQDLEIEIQPASGDSAYQVKVTTNTKKITDDDLTMYWDDVKEQPFLQYHTHKDGVLVINIEDDRIRAIYDGQRFVVFTQDYRNSTRGICGRMSGEQRDDYLTPEGLVDKPELYAAAYSLNEENSDPKTQELKALATQQAYYPEYKYTSILRSDPTWQEESQSCGEDQWQSETVYKSRSYDKHKGACEVRQQVQFYENHGDICITTSRVPSCQSHCRAGDYKIQHVQVTCKSKLDHDFRMYKEQIKKGQNPEVSGIPSVKQFKVPVTCQP
Sequence map45-42
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA