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13413 details
Primary information
ID13413
Uniprot IDM0R8L2
DescriptionSpexin (Liver regeneration-related protein LRRGT00060) (NPQ) (Neuropeptide Q) (Spexin hormone) [Cleaved into- Spexin-1; Spexin-2 (NPQ 53-70)]
OrganismRattus norvegicus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the spexin family.
Tissue SpecificityWidely expressed; predominantly expressed in epithelial cells in the skin; respiratory; digestive; urinary and reproductive systems; retina; adrenal gland and various brain regions. In the adrenal gla
Post Translational ModificationNA
FunctionPlays a role as a central modulator of cardiovascular and renal function and nociception. Plays also a role in energy metabolism and storage. Inhibits adrenocortical cell proliferation with minor stimulation on corticosteroid release
Length116
Molecular Weight13
NameSpexin
SequencePQRLSEKRNWTPQAMLYLKGAQGHRFISDQSRRKELADRPPPERRNPNLQLLTLPEAAALFLASLEKPQKDEGGDFDKSKLLEDRRFYW
Sequence map28-56
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA