Primary information |
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ID | 13367 |
Uniprot ID | O35417 |
Description | Proenkephalin-B (Beta-neoendorphin-dynorphin) (Preprodynorphin) [Cleaved into- Alpha-neoendorphin; Beta-neoendorphin; Big dynorphin (Big Dyn); Dynorphin A(1-17) (Dyn-A17) (Dynorphin A); Dynorphin A(1-13); Dynorphin A(1-8); Leu-enkephalin; Rimorphin (Dynorphin B) (Dyn-B) (Dynorphin B(1-13)); Leumorph |
Organism | Mus musculus |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus (Mouse) |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | Belongs to the opioid neuropeptide precursor family. |
Tissue Specificity | NA |
Post Translational Modification | The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing. |
Function | Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions; including pain perception and responses to stress. |
Length | 248 |
Molecular Weight | 28 |
Name | Proenkephalin-B |
Sequence | YGGFLRRIRPKLK |
Sequence map | 312 |
PDB ID | 9751516; 2409273; 16292317 |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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