| Primary information |
|---|
| ID | 13363 |
| Uniprot ID | O15130 |
| Description | Pro-FMRFamide-related neuropeptide FF (FMRFamide-related peptides) [Cleaved into- Neuropeptide SF (NPSF); Neuropeptide FF (NPFF); Neuropeptide AF (NPAF)] |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the FARP (FMRFamide related peptide) family. |
| Tissue Specificity | NA |
| Post Translational Modification | NA |
| Function | Morphine modulating peptides. Have wide-ranging physiologic effects; including the modulation of morphine-induced analgesia; elevation of arterial blood pressure; and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels. |
| Length | 113 |
| Molecular Weight | 12 |
| Name | Pro-FMRFamide-related neuropeptide FF |
| Sequence | SQAFLFQPQRF |
| Sequence map | 264 |
| PDB ID | 9224703; 16541075; 15489334; 11587714 |
| Drugpedia | NA |
| Receptor | Q9GZQ6; Q9Y5X5 |
| Domain | NA |
| Pharmaceutical Use | NA
|