Detailed description page of Hmrbase2

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13357 details
Primary information
ID13357
Uniprot IDQ9TR93
DescriptionPeptide YY (PYY) (PYY-I) (Peptide tyrosine tyrosine) [Cleaved into- Peptide YY(3-36) (PYY-II)]
OrganismOryctolagus cuniculus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Lagomorpha; Leporidae (rabbits and hares); Oryctolagus; Oryctolagus cuniculus (Rabbit)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the NPY family.
Tissue SpecificityNA
Post Translational ModificationThe peptide YY form is cleaved at Pro-2 by the prolyl endopeptidase FAP (seprase) activity (in vitro) to generate peptide YY(3-36).
FunctionThis gut peptide inhibits exocrine pancreatic secretion; has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
Length36
Molecular Weight4
NamePeptide YY
SequenceYPSKPEAPGEDASPEELNRYYASLRHYLNLVTRQRY
Sequence map864
PDB ID7984499
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA