| Primary information |
|---|
| ID | 13356 |
| Uniprot ID | Q9UHF0 |
| Description | Tachykinin-3 (ZNEUROK1) [Cleaved into- Neurokinin-B (NKB) (Neuromedin-K)] |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | In pregnancy; the expression of NKB is confined to the outer syncytiotrophoblast of the placenta; significant concentrations of NKB can be detected in plasma as early as week 9; and plasma concentrati |
| Similarity | Belongs to the tachykinin family. |
| Tissue Specificity | NA |
| Post Translational Modification | NA |
| Function | Tachykinins are active peptides which excite neurons; evoke behavioral responses; are potent vasodilators and secretagogues; and contract (directly or indirectly) many smooth muscles. Is a critical central regulator of gonadal function. |
| Length | 121 |
| Molecular Weight | 13 |
| Name | Tachykinin-3 |
| Sequence | DMHDFFVGLM |
| Sequence map | 240 |
| PDB ID | 10866201; 12975309; 15489334; 19079066; 23643382 |
| Drugpedia | 1P9F; |
| Receptor | P21452; P29371; P25103 |
| Domain | NA |
| Pharmaceutical Use | NA
|