| Primary information |
|---|
| ID | 13355 |
| Uniprot ID | P10082 |
| Description | Peptide YY (PYY) (PYY-I) (Peptide tyrosine tyrosine) [Cleaved into- Peptide YY(3-36) (PYY-II)] |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the NPY family. |
| Tissue Specificity | NA |
| Post Translational Modification | The peptide YY form is cleaved at Pro-30 by the prolyl endopeptidase FAP (seprase) activity (in vitro) to generate peptide YY(3-36). |
| Function | This gut peptide inhibits exocrine pancreatic secretion; has a vasoconstrictory action and inhibitis jejunal and colonic mobility. |
| Length | 97 |
| Molecular Weight | 11 |
| Name | Peptide YY |
| Sequence | IKPEAPREDASPEELNRYYASLRHYLNLVTRQRY |
| Sequence map | 816 |
| PDB ID | 8318545; 16625196; 15489334; 3202875; 2587421; 21314817; 16819834 |
| Drugpedia | 2DEZ;2DF0;2L60;2NA5; |
| Receptor | P25929; P49146; P50391; Q15761; P49146; P50391; Q15761 |
| Domain | NA |
| Pharmaceutical Use | NA
|