| Primary information |
|---|
| ID | 13307 |
| Uniprot ID | P01304 |
| Description | Pro-neuropeptide Y [Cleaved into- Neuropeptide Y (Neuropeptide tyrosine) (NPY); C-flanking peptide of NPY (CPON)] (Fragment) |
| Organism | Sus scrofa |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Artiodactyla; Suina; Suidae (pigs); Sus; Sus scrofa (Pig) |
| Subcellular Location | Secreted Cytoplasmic vesicle; secretory vesicle; neuronal dense core vesicle |
| Developmental Stage | NA |
| Similarity | Belongs to the NPY family. |
| Tissue Specificity | One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla. |
| Post Translational Modification | The neuropeptide Y form is cleaved at Pro-11 by the prolyl endopeptidase FAP (seprase) activity (in vitro). |
| Function | NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. |
| Length | 76 |
| Molecular Weight | 8 |
| Name | Pro-neuropeptide Y |
| Sequence | YPSKPDNPGEDAPAEDLARYYSALRHYINLITRQRY |
| Sequence map | 864 |
| PDB ID | 6957876; 2372534; 1576993 |
| Drugpedia | 1F8P;1FVN;1ICY;1TZ4;1TZ5; |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|