Detailed description page of Hmrbase2

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13297 details
Primary information
ID13297
Uniprot IDQ9JI85
DescriptionNucleobindin-2 (DNA-binding protein NEFA) (Prepronesfatin) [Cleaved into- Nesfatin-1]
OrganismRattus norvegicus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat)
Subcellular LocationGolgi apparatus
Developmental StageNA
SimilarityBelongs to the nucleobindin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionCalcium-binding protein which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3
Length420
Molecular Weight50
NameNucleobindin-2
SequenceVPIDVDKTKVHNVEPVESARIEPPDTGLYYDEYLKQVIEVLETDPHFREKLQKADIEEIRSGRLSQELDLVSHKVRTRLDEL
Sequence map1968
PDB ID15489334; 17036007; 21653697; 22293188; 22673903
DrugpediaNA
ReceptorNA
DomainThe GBA (G-alpha binding and activating) motif med
Pharmaceutical UseNA