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13282 details
Primary information
ID13282
Uniprot IDQ9WVA8
DescriptionPro-FMRFamide-related neuropeptide FF (FMRFamide-related peptides) [Cleaved into- Neuropeptide SF (NPSF); Neuropeptide FF (NPFF); Neuropeptide AF-like (NPAF)]
OrganismMus musculus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus (Mouse)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the FARP (FMRFamide related peptide) family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionMorphine modulating peptides. Have wide-ranging physiologic effects; including the modulation of morphine-induced analgesia; elevation of arterial blood pressure; and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels.
Length114
Molecular Weight13
NamePro-FMRFamide-related neuropeptide FF
SequenceFLFQPQRF
Sequence map192
PDB ID10220558; 10798398
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA