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13259 details
Primary information
ID13259
Uniprot IDQ99MP5
DescriptionPromotilin [Cleaved into- Motilin; Motilin-associated peptide (MAP)]
OrganismCavia porcellus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Hystricomorpha; Caviidae (cavies); Cavia (guinea pigs); Cavia porcellus (Guinea pig)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the motilin family.
Tissue SpecificityPresent in the gut mucosa with the exception of the gastric corpus. Also present in medulla oblongata; nucleus of the solitary tract; hypophysis; spinal cord; hypothalamus; and cerebellum but not in t
Post Translational ModificationNA
FunctionPlays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
Length127
Molecular Weight14
NamePromotilin
SequenceSLRVQQRSKAAGRLEPQEVMEEEENGVIKLTAPVEIGVGLSSRQLEKHRAVLEALLSEALPPPSLVFGGQRPVTAAWE
Sequence map1872
PDB ID11172801
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA