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13256 details
Primary information
ID13256
Uniprot IDP0DJ95
DescriptionPituitary adenylate cyclase-activating polypeptide (PACAP) [Cleaved into- PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)] (Fragments)
OrganismHeloderma suspectum
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria (diapsids); Lepidosauria (lepidosaurs); Squamata (squamates); Bifurcata (split-tongued squamates); Unidentata; Episquamata; Toxicofera; Anguimorpha (anguimorph lizards); Neoanguimorpha (New World anguimorph lizards); Helodermatidae (beaded lizards); Heloderma;
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the glucagon family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionBinding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development.
Length56
Molecular Weight6
NamePituitary adenylate cyclase-activating polypeptide
SequenceHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQ
Sequence map792
PDB ID9545315
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA