Detailed description page of Hmrbase2

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13199 details
Primary information
ID13199
Uniprot IDP22466
DescriptionGalanin peptides [Cleaved into- Galanin; Galanin message-associated peptide (GMAP)]
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the galanin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionEndocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1; GALR2; and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract; growth hormone and insulin release and adrenal secretion.
Length123
Molecular Weight13
NameGalanin peptides
SequenceELRPEDDMKPGSFDRSIPENNIMRTIIEFLSFLHLKEAGALDRLLDLPAAASSEDIERS
Sequence map1416
PDB ID7508413; 1370155; 15489334; 1710578; 1722333; 14997482; 16807684; 18669648; 21406692; 23186
DrugpediaNA
ReceptorP47211; O43603; O60755
DomainNA
Pharmaceutical UseNA