| Primary information |
|---|
| ID | 13183 |
| Uniprot ID | P12760 |
| Description | Neuromedin-U [Cleaved into- Neuromedin precursor-related peptide 36 (NURP36); Neuromedin precursor-related peptide 33 (NURP33); Neuromedin-U-23 (NmU-23)] |
| Organism | Rattus norvegicus |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat) |
| Subcellular Location | [Neuromedin-U-23]- Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the NmU family. |
| Tissue Specificity | Expressed throughout the gastrointestinal tract with highest levels in the duodenum and jejunum (PubMed-7916966). Low levels in spinal cord; hypothalamus; and stomach (PubMed-7916966). Neuromedin-U-23 |
| Post Translational Modification | NA |
| Function | [Neuromedin-U-23]- Ligand for receptors NMUR1 and NMUR2 |
| Length | 174 |
| Molecular Weight | 19 |
| Name | Neuromedin-U |
| Sequence | YKVNEYQGPVAPSGGFFLFRPRN |
| Sequence map | 552 |
| PDB ID | 1448109; 28874765; 3178840; 3411332; 7916966; 15635449 |
| Drugpedia | NA |
| Receptor | Q9ESQ4; Q9JJI5 |
| Domain | NA |
| Pharmaceutical Use | NA
|