| Primary information |
|---|
| ID | 13165 |
| Uniprot ID | Q3E880 |
| Description | Protein GOLVEN 11 (CLAVATA3/ESR (CLE)-related protein CLEL8) (CLE-Like protein 8) (Root meristem growth factor 1) (AtRGF1) [Cleaved into- GLV11p (RGF1p)] |
| Organism | Arabidopsis thaliana |
| Txonomy | Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliopsida; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis; Arabidopsis thaliana (Mouse-ear cress) |
| Subcellular Location | [GLV11p]- Secreted |
| Developmental Stage | In roots; expressed only in the quiescent center (QC) and the columella stem cells (CC) initials (PubMed-20798316; PubMed-23370719). Induced during lateral root formation (PubMed-23370719). |
| Similarity | Belongs to the RGF family. |
| Tissue Specificity | Expressed in root tips; only in the quiescent center and the columella stem cells. |
| Post Translational Modification | The tyrosine sulfation is critical for the function of the peptide. |
| Function | [GLV11p]- Acts as a peptide hormone recognized by receptors (e.g. RGI1 and RGI2) to trigger signaling events including the regulation of RITF1 expression and leading to the production of reactive oxygen species (ROS) in roots to modulate meristem size |
| Length | 116 |
| Molecular Weight | 13 |
| Name | Protein GOLVEN 11 |
| Sequence | DYSNPGHHPPRHN |
| Sequence map | 312 |
| PDB ID | 20798316; 9872454; 27862469; 17147637; 22307643; 23370719; 25856240; 27229312; 27001831; 31 |
| Drugpedia | 5HYX; |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|