| Primary information |
|---|
| ID | 13134 |
| Uniprot ID | Q62949 |
| Description | Cortistatin [Cleaved into- Cortistatin-29; Cortistatin-14] |
| Organism | Rattus norvegicus |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat) |
| Subcellular Location | Secreted |
| Developmental Stage | There is a transient increase in cortistatin-expressing cells in the second postnatal week in all cortical areas and in the dentate gyrus. A transient expression is observed in the hilar region at P16 |
| Similarity | Belongs to the somatostatin family. |
| Tissue Specificity | Interneurons in the cerebral cortex and hyppocampus. |
| Post Translational Modification | NA |
| Function | Neuropeptide with neuronal depressant and sleep-modulating properties. |
| Length | 112 |
| Molecular Weight | 12 |
| Name | Cortistatin |
| Sequence | PCKNFFWKTFSSCK |
| Sequence map | 336 |
| PDB ID | 8622767 |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|