Detailed description page of Hmrbase2

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13134 details
Primary information
ID13134
Uniprot IDQ62949
DescriptionCortistatin [Cleaved into- Cortistatin-29; Cortistatin-14]
OrganismRattus norvegicus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat)
Subcellular LocationSecreted
Developmental StageThere is a transient increase in cortistatin-expressing cells in the second postnatal week in all cortical areas and in the dentate gyrus. A transient expression is observed in the hilar region at P16
SimilarityBelongs to the somatostatin family.
Tissue SpecificityInterneurons in the cerebral cortex and hyppocampus.
Post Translational ModificationNA
FunctionNeuropeptide with neuronal depressant and sleep-modulating properties.
Length112
Molecular Weight12
NameCortistatin
SequencePCKNFFWKTFSSCK
Sequence map336
PDB ID8622767
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA