Primary information |
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ID | 13134 |
Uniprot ID | Q62949 |
Description | Cortistatin [Cleaved into- Cortistatin-29; Cortistatin-14] |
Organism | Rattus norvegicus |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat) |
Subcellular Location | Secreted |
Developmental Stage | There is a transient increase in cortistatin-expressing cells in the second postnatal week in all cortical areas and in the dentate gyrus. A transient expression is observed in the hilar region at P16 |
Similarity | Belongs to the somatostatin family. |
Tissue Specificity | Interneurons in the cerebral cortex and hyppocampus. |
Post Translational Modification | NA |
Function | Neuropeptide with neuronal depressant and sleep-modulating properties. |
Length | 112 |
Molecular Weight | 12 |
Name | Cortistatin |
Sequence | PCKNFFWKTFSSCK |
Sequence map | 336 |
PDB ID | 8622767 |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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