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13133 details
Primary information
ID13133
Uniprot IDQ5W1L4
DescriptionPro-corazonin (Crz) (De-Crz) [Cleaved into- Corazonin; Corazonin precursor-related peptide (CPRP)]
OrganismDrosophila erecta
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota (winged insects); Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Eremoneura; Cyclorrhapha; Schizophora; Acalyptratae; Ephydroidea; Drosophilidae (pomace flies); Drosophilinae; Drosophilini; Drosophila (fruit flies); Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta (Fruit fly)
Subcellular Location[Corazonin]- Secreted
Developmental StageNA
SimilarityBelongs to the corazonin family.
Tissue SpecificityExpression is restricted to 24 neurons in the larval CNS (8 in the brain and 16 in the ventral nerve cord) and 12-16 neurons in the pars lateralis of the adult brain.
Post Translational ModificationNA
FunctionCardioactive peptide. Corazonin is probably involved in the physiological regulation of the heart beat. Clock (Clk) and cycle (cyc) proteins negatively regulate Crz transcription in a cell-specific manner.
Length154
Molecular Weight17
NamePro-corazonin
SequenceSFNAASPLLTTGHLHRGSELGLSDLYDLQEWTSD
Sequence map816
PDB ID15669053
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA