| Primary information |
|---|
| ID | 13119 |
| Uniprot ID | P01183 |
| Description | Vasopressin-neurophysin 2-copeptin (AVP-NPII) [Cleaved into- Lys-vasopressin; Neurophysin 2 (Neurophysin-I/-III); Copeptin] |
| Organism | Sus scrofa |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Artiodactyla; Suina; Suidae (pigs); Sus; Sus scrofa (Pig) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the vasopressin/oxytocin family. |
| Tissue Specificity | NA |
| Post Translational Modification | A shorter neurophysin molecule (32-123) is called neurophysin-I and is derived from the complete protein (called neurophysin III) by proteolytic degradation (in vivo or after extraction). |
| Function | Neurophysin 2 specifically binds vasopressin.; Vasopressin has a direct antidiuretic action on the kidney; it also causes vasoconstriction of the peripheral vessels. Acts by binding to vasopressin receptors (V1bR/AVPR1B; V1aR/AVPR1A; and V2R/AVPR2). |
| Length | 166 |
| Molecular Weight | 17 |
| Name | Vasopressin-neurophysin 2-copeptin |
| Sequence | AMSDLELRQCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCNDESCVTEPECREGASFLRRA |
| Sequence map | 2280 |
| PDB ID | 3768139; 1971513; 4940405; 944186; 1001445; 465021; 4673067 |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
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