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13101 details
Primary information
ID13101
Uniprot IDP01181
DescriptionVasopressin-neurophysin 2-copeptin (AVP-NPII) [Cleaved into- Arg-vasopressin (Arginine-vasopressin); Neurophysin 2 (Neurophysin-III); Copeptin] (Fragment)
OrganismOvis aries
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis; Ovis aries (Sheep)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the vasopressin/oxytocin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionNeurophysin 2 specifically binds vasopressin.; Vasopressin has a direct antidiuretic action on the kidney; it also causes vasoconstriction of the peripheral vessels. Acts by binding to vasopressin receptors (V1bR/AVPR1B; V1aR/AVPR1A; and V2R/AVPR2).
Length147
Molecular Weight15
NameVasopressin-neurophysin 2-copeptin
SequenceAMSDLELRQCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCQEEIYLPSPCQSGQKPCGSGGRCAAAGICCNDESCVTEPECREGIGFPRRV
Sequence map2280
PDB ID1236812; 465021
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA