| Primary information |
|---|
| ID | 13075 |
| Uniprot ID | P01364 |
| Description | Abdominal ganglion neuropeptide R3-14 [Cleaved into- Histidine-rich basic peptide (HRBP); Peptide I; Peptide II] |
| Organism | Aplysia californica |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Mollusca; Gastropoda; Heterobranchia; Euthyneura; Tectipleura; Aplysiida (sea hares); Aplysioidea; Aplysiidae; Aplysia; Aplysia californica (California sea hare) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | NA |
| Tissue Specificity | Neurons R3-R14. A cluster of 12 giant neurons located on the right side of the abdominal ganglion. |
| Post Translational Modification | The partial formation of pyroglutamate from N-terminal glutamic acid in peptides isolated from single cells is detected by mass spectrometry (PubMed-9930740). There are indications this modification d |
| Function | HRBP is a myoactive peptide that excites Aplysia heart and enhances gut motility in vitro. |
| Length | 108 |
| Molecular Weight | 12 |
| Name | Abdominal ganglion neuropeptide R3-14 |
| Sequence | EAEEPSAFMTRL |
| Sequence map | 288 |
| PDB ID | 6194901; 6474178; 2573895; 3549995; 9930740 |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|