Primary information |
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ID | 13073 |
Uniprot ID | P01364 |
Description | Abdominal ganglion neuropeptide R3-14 [Cleaved into- Histidine-rich basic peptide (HRBP); Peptide I; Peptide II] |
Organism | Aplysia californica |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Mollusca; Gastropoda; Heterobranchia; Euthyneura; Tectipleura; Aplysiida (sea hares); Aplysioidea; Aplysiidae; Aplysia; Aplysia californica (California sea hare) |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | NA |
Tissue Specificity | Neurons R3-R14. A cluster of 12 giant neurons located on the right side of the abdominal ganglion. |
Post Translational Modification | The partial formation of pyroglutamate from N-terminal glutamic acid in peptides isolated from single cells is detected by mass spectrometry (PubMed-9930740). There are indications this modification d |
Function | HRBP is a myoactive peptide that excites Aplysia heart and enhances gut motility in vitro. |
Length | 108 |
Molecular Weight | 12 |
Name | Abdominal ganglion neuropeptide R3-14 |
Sequence | QVAQMHVWRAVNHDRNHGTGSGRHGRFLIRNRYRYGGGHLSDA |
Sequence map | 1032 |
PDB ID | 6194901; 6474178; 2573895; 3549995; 9930740 |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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