| Primary information |
|---|
| ID | 13042 |
| Uniprot ID | P55207 |
| Description | C-type natriuretic peptide [Cleaved into- CNP-22; CNP-29; CNP-53] |
| Organism | Rattus norvegicus |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the natriuretic peptide family. |
| Tissue Specificity | Expressed exclusively in brain. |
| Post Translational Modification | [CNP-22]- Degraded by IDE (in vitro). |
| Function | [CNP-22]- Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Acts by specifically binding and stimulating NPR2 to produce cGMP. Binds the clearance receptor NPR3. |
| Length | 126 |
| Molecular Weight | 13 |
| Name | C-type natriuretic peptide |
| Sequence | GLSKGCFGLKLDRIGSMSGLGC |
| Sequence map | 528 |
| PDB ID | 1702395 |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|