Detailed description page of Hmrbase2

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13017 details
Primary information
ID13017
Uniprot IDP09558
DescriptionEndothelin-1 (ET-1) (Preproendothelin-1) (PPET1) [Cleaved into- Big endothelin-1]
OrganismSus scrofa
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Artiodactyla; Suina; Suidae (pigs); Sus; Sus scrofa (Pig)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the endothelin/sarafotoxin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionEndothelins are endothelium-derived vasoconstrictor peptides
Length203
Molecular Weight23
NameEndothelin-1
SequenceCSCSSLMDKECVYFCHLDIIW
Sequence map504
PDB ID2451132; 2669747; 2665739; 2205205
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA