| Primary information |
|---|
| ID | 13001 |
| Uniprot ID | P83659 |
| Description | Cyphokinin (Bradykinin-related peptide) [Cleaved into- Thr6-bradykinin (Thr6-BK)] |
| Organism | Cyphononyx dorsalis |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Panarthropoda; Arthropoda; Mandibulata; Pancrustacea; Hexapoda; Insecta; Dicondylia; Pterygota (winged insects); Neoptera; Endopterygota; Hymenoptera; Apocrita (wasps; ants; and bees); Aculeata; Pompiloidea; Pompilidae (spider wasps); Pepsinae; Cyphononyx; Cyphononyx dorsalis (Spider wasp) (Cyphononyx fulvognathus) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the bradykinin-related peptide family. |
| Tissue Specificity | Expressed by the venom gland. |
| Post Translational Modification | NA |
| Function | [Cyphokinin]- inhibits angiotensin-converting enzyme (ACE) with a Ki of 2.2 uM and targets B2 bradykinin receptor (BDKRB2). Also provokes contraction of smooth muscle preparation (ileum). In vivo; induces hyperalgesic effects in living rats after intraplantar injection. |
| Length | 11 |
| Molecular Weight | 1 |
| Name | Cyphokinin |
| Sequence | DTRPPGFTPFR |
| Sequence map | 264 |
| PDB ID | 19716363; 11306139; 27096870 |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|