Primary information |
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ID | 12964 |
Uniprot ID | Q76IQ4 |
Description | Ghrelin [Cleaved into- Ghrelin-23; Ghrelin-24] |
Organism | Oncorhynchus mykiss |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Euteleosteomorpha; Protacanthopterygii; Salmoniformes (salmons and trouts); Salmonidae (salmonids); Salmoninae (trouts; salmons & chars); Oncorhynchus; Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | Belongs to the motilin family. |
Tissue Specificity | Highest levels in the stomach. Moderate levels in the brain; hypothalamus and intestinal tracts. |
Post Translational Modification | O-octanoylation or O-decanoylation is essential for activity. The O-decanoylated forms differ in the length of the carbon backbone of the carboxylic acid forming an ester bond with Ser-29. The majorit |
Function | Ligand for growth hormone secretagogue receptor type 1 (GHSR). Has an appetite-stimulating effect; induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Induces the release of growth hormone from the pituitary. |
Length | 111 |
Molecular Weight | 12 |
Name | Ghrelin |
Sequence | GSSFLSPSQKPQVRQGKGKPPRVG |
Sequence map | 576 |
PDB ID | 12970156 |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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