| Primary information |
|---|
| ID | 12963 |
| Uniprot ID | Q76IQ4 |
| Description | Ghrelin [Cleaved into- Ghrelin-23; Ghrelin-24] |
| Organism | Oncorhynchus mykiss |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Euteleosteomorpha; Protacanthopterygii; Salmoniformes (salmons and trouts); Salmonidae (salmonids); Salmoninae (trouts; salmons & chars); Oncorhynchus; Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the motilin family. |
| Tissue Specificity | Highest levels in the stomach. Moderate levels in the brain; hypothalamus and intestinal tracts. |
| Post Translational Modification | O-octanoylation or O-decanoylation is essential for activity. The O-decanoylated forms differ in the length of the carbon backbone of the carboxylic acid forming an ester bond with Ser-29. The majorit |
| Function | Ligand for growth hormone secretagogue receptor type 1 (GHSR). Has an appetite-stimulating effect; induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Induces the release of growth hormone from the pituitary. |
| Length | 111 |
| Molecular Weight | 12 |
| Name | Ghrelin |
| Sequence | GSSFLSPSQKPQVRQGKGKPPRV |
| Sequence map | 552 |
| PDB ID | 12970156 |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|