Detailed description page of Hmrbase2

This page displays user query in tabular form.

12918 details
Primary information
ID12918
Uniprot IDQ8CE23
DescriptionOrexigenic neuropeptide QRFP (P518) [Cleaved into- QRF-amide (Neuropeptide RF-amide) (Pyroglutamylated arginine-phenylalanine-amide peptide)]
OrganismMus musculus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus (Mouse)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the RFamide neuropeptide family.
Tissue SpecificityExpressed in the brain with highest levels in the periventricular hypothalamic nucleus and lateral hypothalamic areas. Expressed at moderate levels in the adrenal gland; eye; heart; intestine; liver;
Post Translational ModificationNA
FunctionStimulates feeding and grooming behavior; metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland.
Length124
Molecular Weight13
NameOrexigenic neuropeptide QRFP
SequenceQDGSSEAAGFLPADSEKASGPLGTLAEELSSYSRRKGGFSFRF
Sequence map1032
PDB ID12714592; 12960173; 16141072; 19468303; 16648250
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA