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12890 details
Primary information
ID12890
Uniprot IDP18104
DescriptionC-type natriuretic peptide [Cleaved into- CNP-22; CNP-29; CNP-53]
OrganismSus scrofa
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Artiodactyla; Suina; Suidae (pigs); Sus; Sus scrofa (Pig)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the natriuretic peptide family.
Tissue SpecificityNA
Post Translational Modification[CNP-22]- Degraded by IDE (in vitro).
Function[CNP-22]- Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Acts by specifically binding and stimulating NPR2 to produce cGMP. Binds the clearance receptor NPR3.
Length126
Molecular Weight13
NameC-type natriuretic peptide
SequenceGLSKGCFGLKLDRIGSMSGLGC
Sequence map528
PDB ID2146957; 2383278; 2139780
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA