Primary information |
---|
ID | 12884 |
Uniprot ID | P01283 |
Description | VIP peptides [Cleaved into- Intestinal peptide PHV-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)] |
Organism | Rattus norvegicus |
Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat) |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | Belongs to the glucagon family. |
Tissue Specificity | NA |
Post Translational Modification | NA |
Function | VIP causes vasodilation; lowers arterial blood pressure; stimulates myocardial contractility; increases glycogenolysis and relaxes the smooth muscle of trachea; stomach and gall bladder.; PHM-27 is a potent agonist of the calcitonin receptor CALCR; with similar efficacy as calcitonin. PHI also causes vasodilation. |
Length | 170 |
Molecular Weight | 19 |
Name | VIP peptides |
Sequence | HSDAVFTDNYTRLRKQMAVKKYLNSILN |
Sequence map | 672 |
PDB ID | 2159586; 3838518; 1851524; 3379062; 8402943; 22673903 |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
|