Detailed description page of Hmrbase2

This page displays user query in tabular form.

12884 details
Primary information
ID12884
Uniprot IDP01283
DescriptionVIP peptides [Cleaved into- Intestinal peptide PHV-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)]
OrganismRattus norvegicus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the glucagon family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionVIP causes vasodilation; lowers arterial blood pressure; stimulates myocardial contractility; increases glycogenolysis and relaxes the smooth muscle of trachea; stomach and gall bladder.; PHM-27 is a potent agonist of the calcitonin receptor CALCR; with similar efficacy as calcitonin. PHI also causes vasodilation.
Length170
Molecular Weight19
NameVIP peptides
SequenceHSDAVFTDNYTRLRKQMAVKKYLNSILN
Sequence map672
PDB ID2159586; 3838518; 1851524; 3379062; 8402943; 22673903
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA