| Primary information |
|---|
| ID | 12883 |
| Uniprot ID | P01283 |
| Description | VIP peptides [Cleaved into- Intestinal peptide PHV-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)] |
| Organism | Rattus norvegicus |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the glucagon family. |
| Tissue Specificity | NA |
| Post Translational Modification | NA |
| Function | VIP causes vasodilation; lowers arterial blood pressure; stimulates myocardial contractility; increases glycogenolysis and relaxes the smooth muscle of trachea; stomach and gall bladder.; PHM-27 is a potent agonist of the calcitonin receptor CALCR; with similar efficacy as calcitonin. PHI also causes vasodilation. |
| Length | 170 |
| Molecular Weight | 19 |
| Name | VIP peptides |
| Sequence | HADGVFTSDYSRLLGQISAKKYLESLI |
| Sequence map | 648 |
| PDB ID | 2159586; 3838518; 1851524; 3379062; 8402943; 22673903 |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|