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12859 details
Primary information
ID12859
Uniprot IDP01282
DescriptionVIP peptides [Cleaved into- Intestinal peptide PHV-42 (Peptide histidine valine 42); Intestinal peptide PHM-27 (Peptide histidine methioninamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)]
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the glucagon family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionVIP causes vasodilation; lowers arterial blood pressure; stimulates myocardial contractility; increases glycogenolysis and relaxes the smooth muscle of trachea; stomach and gall bladder.
Length170
Molecular Weight19
NameVIP peptides
SequenceHADGVFTSDFSKLLGQLSAKKYLESLM
Sequence map648
PDB ID6571696; 3899557; 2995945; 3025882; 2839091; 14574404; 15489334; 3748844; 6139527; 2434617;
Drugpedia2RRH;2RRI;
ReceptorP30988; P32241; P41587
DomainNA
Pharmaceutical UseNA