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12836 details
Primary information
ID12836
Uniprot IDQ9EPS2
DescriptionPeptide YY (PYY) (Peptide tyrosine tyrosine) [Cleaved into- Peptide YY(3-36) (PYY-II)]
OrganismMus musculus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus (Mouse)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the NPY family.
Tissue SpecificityNA
Post Translational ModificationThe peptide YY form is cleaved at Pro-30 by the prolyl endopeptidase FAP (seprase) activity (in vitro) to generate peptide YY(3-36).
FunctionThis gut peptide inhibits exocrine pancreatic secretion; has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
Length98
Molecular Weight11
NamePeptide YY
SequenceYPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY
Sequence map864
PDB ID15489334;
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA