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12812 details
Primary information
ID12812
Uniprot IDQ9XSW6
DescriptionPro-neuropeptide Y [Cleaved into- Neuropeptide Y (Neuropeptide tyrosine) (NPY); C-flanking peptide of NPY (CPON)]
OrganismMacaca mulatta
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae (Old World monkeys); Cercopithecinae; Macaca (macaques); Macaca mulatta (Rhesus macaque)
Subcellular LocationSecreted Cytoplasmic vesicle; secretory vesicle; neuronal dense core vesicle
Developmental StageNA
SimilarityBelongs to the NPY family.
Tissue SpecificityNA
Post Translational ModificationThe neuropeptide Y form is cleaved at Pro-30 by the prolyl endopeptidase FAP (seprase) activity (in vitro).
FunctionNPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
Length97
Molecular Weight10
NamePro-neuropeptide Y
SequenceYPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY
Sequence map864
PDB ID14718659
Drugpedia1R9N;
ReceptorNA
DomainNA
Pharmaceutical UseNA