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12805 details
Primary information
ID12805
Uniprot IDP68005
DescriptionPeptide YY (PYY) (Peptide tyrosine tyrosine) [Cleaved into- Peptide YY(3-36) (PYY-II)]
OrganismSus scrofa
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Artiodactyla; Suina; Suidae (pigs); Sus; Sus scrofa (Pig)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the NPY family.
Tissue SpecificityNA
Post Translational ModificationThe peptide YY form is cleaved at Pro-2 by the prolyl endopeptidase FAP (seprase) activity (in vitro) to generate peptide YY(3-36).
FunctionThis gut peptide inhibits exocrine pancreatic secretion; has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
Length36
Molecular Weight4
NamePeptide YY
SequenceYPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY
Sequence map864
PDB ID6953409; 11248248; 10933813; 15178255
Drugpedia1QBF;1RU5;1RUU;2OON;2OOP;2RLK;
ReceptorNA
DomainNA
Pharmaceutical UseNA