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12804 details
Primary information
ID12804
Uniprot IDP32648
DescriptionVIP peptides [Cleaved into- Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)]
OrganismMus musculus
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus (Mouse)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the glucagon family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionVIP causes vasodilation; lowers arterial blood pressure; stimulates myocardial contractility; increases glycogenolysis and relaxes the smooth muscle of trachea; stomach and gall bladder.; PHM-27 is a potent agonist of the calcitonin receptor CALCR; with similar efficacy as calcitonin. PHM also causes vasodilation.
Length170
Molecular Weight19
NameVIP peptides
SequenceHSDAVFTDNYTRLRKQMAVKKYLNSILN
Sequence map672
PDB ID1851524; 16141072; 15489334; 7894056; 8402943
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA