| Primary information |
|---|
| ID | 12758 |
| Uniprot ID | Q3YBN2 |
| Description | Tear acid lipase-like protein (TALLP) |
| Organism | Mesocricetus auratus |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Cricetidae; Cricetinae (hamsters); Mesocricetus; Mesocricetus auratus (Golden hamster) |
| Subcellular Location | Secreted |
| Developmental Stage | Expressed primarily during lactation although very low levels are detected in a small percentage of non-lactating females (at protein level). Not expressed in late-pregnant or 1-day postpartum dams bu |
| Similarity | Belongs to the AB hydrolase superfamily. Lipase family. |
| Tissue Specificity | Expressed in female lacrimal gland acinar cells from where it is secreted into tears (at protein level). |
| Post Translational Modification | N-glycosylated. |
| Function | Female-specific protein which lacks detectable lipase activity against a range of substrates. Binds the hydrophobic lipid 1-aminoanthracene with high affinity. |
| Length | 398 |
| Molecular Weight | 44 |
| Name | Tear acid lipase-like protein |
| Sequence | FETTTNPEAYMKVSKIVNHWGYTSEEYEAVTEDGYILPLNRIPHGKNNINSTAPKKVVLCQHGLFSTAGVWVSNPPSNSLAFILADAGFDVWMGNSRGSTWAKKHLYLDPNSKEFWAFSFDEMIKYDLPATINFILKKTGQKQIYYIGHSQGALIALGAFSTNQKLAEKIKLCFLLAPIATLKHVEGIVSLLPYFYPTAFKVVFSEKEFLSAVAFSKLHGYSCNAKVINDGCVAIFLSMTGYVPQHLNKSRVDVYIRHSLAGTSVQTLLHYRQAIKKGVFEAYDWGSQSLNMLHYNQTTPPLYNVEDMKIPTAMWSGGKDSLADTKDVAHLVPKISNLIYHKITADFSHLDFTVGKNAYYVSNDILKLLDKSETENLH |
| Sequence map | 26-38 |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|