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12750 details
Primary information
ID12750
Uniprot IDP30623
DescriptionTransthyretin (Prealbumin) (TBPA)
OrganismTiliqua rugosa
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria (diapsids); Lepidosauria (lepidosaurs); Squamata (squamates); Bifurcata (split-tongued squamates); Unidentata; Scinciformata; Scincidae (skinks); Egerniinae; Tiliqua; Tiliqua rugosa (Shingleback lizard) (Trachydosaurus rugosus)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the transthyretin family.
Tissue SpecificityDetected in choroid plexus (at protein level). Detected in choroid plexus.
Post Translational ModificationNA
FunctionThyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Length150
Molecular Weight16
NameTransthyretin
SequencePLVSHGSIDSKCPLMVKVLDAVRGRPATSIAVKVSKMSEEGDWKEFANGKTNEFGEIHELTTDEQFVQGLYKVEFDTSSYWKALGVSPFHEYADVVFSANDSGHRHYTIAALLSPFSYSTTAVVSDPKE
Sequence map23-30
PDB IDNA
DrugpediaNA
ReceptorNA
DomainThe N-terminus strongly influences thyroid hormone
Pharmaceutical UseNA